TY - JOUR TI - Evaluation of light detector surface area for functional Near Infrared Spectroscopy AU - Wang, Lei AU - Ayaz, Hasan AU - Izzetoglu, Meltem AU - Onaral, Banu T2 - Computers in Biology and Medicine AB - Functional Near Infrared Spectroscopy (fNIRS) is an emerging neuroimaging technique that utilizes near infrared light to detect cortical concentration changes of oxy-hemoglobin and deoxy-hemoglobin non-invasively. Using light sources and detectors over the scalp, multi-wavelength light intensities are recorded as time series and converted to concentration changes of hemoglobin via modified Beer-Lambert law. Here, we describe a potential source for systematic error in the calculation of hemoglobin changes and light intensity measurements. Previous system characterization and analysis studies looked into various fNIRS parameters such as type of light source, number and selection of wavelengths, distance between light source and detector. In this study, we have analyzed the contribution of light detector surface area to the overall outcome. Results from Monte Carlo based digital phantoms indicated that selection of detector area is a critical system parameter in minimizing the error in concentration calculations. The findings here can guide the design of future fNIRS sensors. DA - 2017/10/01/ PY - 2017 DO - 10.1016/j.compbiomed.2017.07.019 DP - ScienceDirect VL - 89 SP - 68 EP - 75 J2 - Computers in Biology and Medicine LA - en SN - 0010-4825 UR - https://www.sciencedirect.com/science/article/pii/S0010482517302433 Y2 - 2022/03/12/02:40:52 KW - Detector surface area KW - Differential pathlength factor KW - Functional Near Infrared Spectroscopy KW - Modified Beer-Lambert law KW - Monte Carlo simulation ER -